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Tag: BIST™ A+

  • HPLC Method for Analysis of  FD&C Yellow 5 (Tartrazine) in M&M’s  on BIST A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies High Performance Liquid Chromatography (HPLC) Method for Analysis of  FD&C Yellow 5 (Tartrazine) Tartrazine is a popular, multi-charged yellow synthetic dye used in a multitude of food and cosmetic products, including colorful sugar-coated chocolate candies. Using SIELC’s newly introduced BIST™ method, tartrazine, which dissolves and […]

  • HPLC Method for Analysis of Quinoline Yellow WS on BIST A+ Column by SIELC Technologies

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Quinoline Yellow WS (E104, D&C Yellow 10) is a mixture of 3 different derivatives of Quinoline Yellow SS, consisting of monosulfonates, (mostly) disulfonates, and trisulfonates. The dye is typically neon-yellow (yellow with a hint of green). Using SIELC’s newly introduced BIST™ method, Quinoline Yellow […]

  • HPLC Method for Analysis of Succinic Acid on BIST A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Methanesulfonic acid is a popular non-volatile catalyst used in organic reactions due to it being a strong acid. Other sulfonic acids, like 1-Pentanesulfonic acid, 1-Heptanesulfonic acid, 1-Decanesulfonic acid, and 1=Dodecanesulfonic acid are typically used in ion chromatography and for organic syntheses. Using SIELC’s newly […]

  • HPLC Method for Analysis of Bivalirudin and Asp9 – bivalirudin on BIST A+

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Bivalirudin is a short, 21-amino-acid peptide.  It has 2 basic and 6 acidic groups. It is a naturally-occurring anticoagulant.  Asp9-bivalirudin is a process impurity and can be a result of the degradation of the drug bivalirudin.  SIELC’s new BIST™ mode can retain and separate Bivalirudin and […]

  • HPLC Method for Analysis of Aconitic Acid on BIST A+

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Aconitic acid is a popular compound used to artificial create nutty flavors in foods. It is also a common intermediate in the Kreb’s cycle when Citrate is changed into D-isocitrate. Using SIELC’s newly introduced BIST™ method, Aconitic acidcan be retained easily on a negatively-charged, […]

  • HPLC Method for Analysis of Sulfonic acids on BIST™ A+ 

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Methanesulfonic acid is a popular non-volatile catalyst used in organic reactions due to it being a strong acid. Other sulfonic acids, like 1-Pentanesulfonic acid, 1-Heptanesulfonic acid, 1-Decanesulfonic acid, and 1=Dodecanesulfonic acid are typically used in ion chromatography and for organic syntheses. Using SIELC’s newly […]

  • HPLC Method for Analysis of Fluoroacetic acid, Difluoroacetic acid and Trifluoroacetic acid on BIST A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Fluoroacetic acid is a toxic metabolite of some drugs that contain fluorine and is a common ingredient in pesticide production. Difluoroacetic acid (DFA) is typically used as a difluoromethylating reagent. Trifluoroacetic acid (TFA) is a popular reagent in organic syntheses and is a popular […]

  • HPLC Method for Analysis of Inorganic anions on BIST™A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Using SIELC’s newly introduced BIST™ method, a mixture of many different inorganic anions can be separated on a negatively-charged, cation-exchange BIST™ A column, contrary to conventional chromatographic wisdom. There are two keys to this retention method: 1) a multi-charged, positive buffer, such as N,N,N’,N’-Tetramethyl-1,3-propanediamine […]

  • HPLC Method for Analysis of Maleic  Acid, Nicotinic Acid, Aconitic Acid and Fumaric Acid on BIST™ A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies The maleate ion from Maleic acid is a popular ingredient as the maleate salt in several different drugs, including Methergine, Pyrilamine, and Carfenazine, among others. Nicotinic acid, also known as Niacin or Vitamin B3, is an essential nutrient for the human body and is […]

  • HPLC Method for Analysis of Chloroacetic acid, Dichloroacetic acid and Trichloroacetic acid on BIST™ A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Chloroacetic acid is a popular building block in organic syntheses. Dichloroacetic acid and Trichloroacetic acid are frequently used in cosmetic treatments to remove tattos and in chemical peels, as well as topical medication for the ablation of warts. Using SIELC’s newly introduced BIST™ method, […]