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HPLC Method for Analysis of Bivalirudin and Asp9 – bivalirudin on BIST A+
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Bivalirudin is a short, 21-amino-acid peptide. It has 2 basic and 6 acidic groups. It is a naturally-occurring anticoagulant. Asp9-bivalirudin is a process impurity and can be a result of the degradation of the drug bivalirudin. SIELC’s new BIST™ mode can retain and separate Bivalirudin and […]
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HPLC Method for Analysis of Enoxaparin on BIST™ A Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies BIST Ionic Modifier Preparation Enoxaparin sodium is a popular anticoagulant used to treat deep vein thrombosis, pulmonary embolisms, and heart attacks. Using SIELC’s newly introduced BIST™ method, Enoxaparin sodium, which ionizes in water, can be retained on a negatively-charged, cation-exchange BIST™ A column. There […]