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HPLC Method for Analysis of Chlorhexidine in Biofluids Blood Plasma and Urine on BIST B+ Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies High Performance Liquid Chromatography (HPLC) Method for Analysis of Chlorhexidine Condition Column BIST™ B+, 4.6×150 mm, 5µm, 100A Mobile Phase Gradient MeCN Buffer H2SO4 – 0.2% Flow Rate 1.0 ml/min Detection UV 260 nm Retention time 6.2 min Description Class of Compounds Topical antiseptic Analyzing […]
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HPLC Method for Analysis of Chlorhexidine on BIST B+ Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies High Performance Liquid Chromatography (HPLC) Method for Analysis of Chlorhexidine Condition Column BIST™ B+, 4.6×150 mm, 5µm, 100A Mobile Phase Gradient MeCN Buffer H2SO4 – 0.2% Flow Rate 1.0 ml/min Detection UV 260 nm Retention time 6.2 min Description Class of Compounds Topical antiseptic Analyzing […]
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HPLC Method for Analysis of Chlorpheniramine Maleate on BIST B+ Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Chlorpheniramine Maleate is a popular antihistamine used to provide relief from the symptoms of allergies, hay fever, and the common cold. Using SIELC’s newly introduced BIST™ method, Chlorpheniramine Maleate, which separates in water, can be retained on a positively-charged anion-exchange BIST™ B column. There […]
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HPLC Method for Analysis of Bivalirudin and Asp9 – bivalirudin on BIST A+
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Bivalirudin is a short, 21-amino-acid peptide. It has 2 basic and 6 acidic groups. It is a naturally-occurring anticoagulant. Asp9-bivalirudin is a process impurity and can be a result of the degradation of the drug bivalirudin. SIELC’s new BIST™ mode can retain and separate Bivalirudin and […]
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HPLC Method for Analysis of Colistin A on BIST B+ Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies View on hplc.cloud Colistin A is a last-resort antibiotic drug sued to treat Gram-negative bacterial infection, such as pneumonia. Using SIELC’s newly introduced BIST™ method, Colistin A can be retained on a positively-charged anion-exchange BIST™ B+ column. There are two keys to this retention […]
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HPLC Method for Analysis of Neurotransmitters Phenylephrine, Epinephrine and Norepinephrine on BIST™B+ Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Epinephrine and norepinephrine are key neurotransmitters and adrenal hormones naturally produced by the body to generate the fight-or-flight response, and synthesized by pharmaceutical companies to treat a host of issues, such as allergic reactions and low blood pressure. Phenylephrine is a related, synthetic compound […]
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HPLC Method for Analysis of Enoxaparin on BIST™ A Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies BIST Ionic Modifier Preparation Enoxaparin sodium is a popular anticoagulant used to treat deep vein thrombosis, pulmonary embolisms, and heart attacks. Using SIELC’s newly introduced BIST™ method, Enoxaparin sodium, which ionizes in water, can be retained on a negatively-charged, cation-exchange BIST™ A column. There […]
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HPLC Method for Analysis of Sulfobutyl ether Beta Cyclodextrin Sodium (SBECD) on BIST™A Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Cyclodextrins are ring-shaped oligosaccharides formed in nature by the digestion of cellulose by bacteria. Cyclodextrins have utility for solubilizing and stabilizing drugs. B-Cyclodextrins sulfobutyl ether is a cyclodextrin made of 7 glucose subunits, each with a negatively-charged sulfobutyl ether group attached. Using SIELC’s newly […]
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HPLC Method for Analysis of Heparin on BIST™ A Column
Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Heparin is a WHO-recognized essential medicine known for its anticoagulant properties and used to treat heart attacks and angina. Due to its very polar and polymeric nature, separating and quantifying Heparin using traditional HPLC methods can be quite difficult. Using SIELC’s newly introduced BIST™ […]