Join our Bridge Ion Separation Technology project at researchgate.net!

Author: admin@sielc.com

  • HPLC Method for Analysis of Enoxaparin on BIST™ A Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies BIST Ionic Modifier Preparation Enoxaparin sodium is a popular anticoagulant used to treat deep vein thrombosis, pulmonary embolisms, and heart attacks. Using SIELC’s newly introduced BIST™ method, Enoxaparin sodium, which ionizes in water, can be retained on a negatively-charged, cation-exchange BIST™ A column. There […]

  • HPLC Method for Analysis of m-Xylylenediamine (MXDA) on BIST™ B+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies m-Xylylenediamine (MXDA) is a popular curing agent used on epoxy resins. Using SIELC’s newly introduced BIST™ method, MXDA, which protonates in water, can be retained on a positively-charged anion-exchange BIST™ B column. There are two keys to this retention method: 1) a multi-charged, negative […]

  • HPLC Method for Analysis of Inorganic anions on BIST™A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Using SIELC’s newly introduced BIST™ method, a mixture of many different inorganic anions can be separated on a negatively-charged, cation-exchange BIST™ A column, contrary to conventional chromatographic wisdom. There are two keys to this retention method: 1) a multi-charged, positive buffer, such as N,N,N’,N’-Tetramethyl-1,3-propanediamine […]

  • HPLC Method for Analysis of Cytochrome C on BIST™ B+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Cytochrome C is a mitochondrial protein that is essential to both the respiratory electron transport chain and the apoptosis cycle of cells. Using SIELC’s newly introduced BIST™ method, this essential protein can be retained on a positively-charged anion-exchange BIST™ B column. There are two […]

  • HPLC Method for Analysis of Maleic  Acid, Nicotinic Acid, Aconitic Acid and Fumaric Acid on BIST™ A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies The maleate ion from Maleic acid is a popular ingredient as the maleate salt in several different drugs, including Methergine, Pyrilamine, and Carfenazine, among others. Nicotinic acid, also known as Niacin or Vitamin B3, is an essential nutrient for the human body and is […]

  • HPLC Method for Analysis of Chloroacetic acid, Dichloroacetic acid and Trichloroacetic acid on BIST™ A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Chloroacetic acid is a popular building block in organic syntheses. Dichloroacetic acid and Trichloroacetic acid are frequently used in cosmetic treatments to remove tattos and in chemical peels, as well as topical medication for the ablation of warts. Using SIELC’s newly introduced BIST™ method, […]

  • HPLC Method for Analysis of Maleic  acid, Ascorbic acid, Nicotinic acid, Fumaric acid and Oxalic acid on BIST™ A+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies The maleate ion from Maleic acid is a popular ingredient as the maleate salt in several different drugs, including Methergine, Pyrilamine, and Carfenazine, among others. Nicotinic acid, also known as Niacin or Vitamin B3, is an essential nutrient for the human body and is […]

  • HPLC Method for Analysis of Insulin on BIST™B+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Insulin is an anabolic peptide hormone naturally produced in the pancreas that regulates the body’s glucose levels. It is also synthesized as a treatment drug for those with Diabetes who can’t regulate their own blood sugar levels naturally. Two well-known forms of synthetic insulin […]

  • HPLC Method for Analysis of PEI on BIST™ B+ Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies High Performance Liquid Chromatography (HPLC) Method for Analysis of PEI Large multi-charged molecules such as polyethyleneimine (PEI) can be very difficult to separate and retain on standard columns. PEI is a complex mixture of the molecules of different sizes and geometry with various biological and […]

  • HPLC Method for Analysis of Sulfobutyl ether Beta Cyclodextrin Sodium (SBECD) on BIST™A Column

    Separation type: Bridge Ion Separation Technology, or BIST™ by SIELC Technologies Cyclodextrins are ring-shaped oligosaccharides formed in nature by the digestion of cellulose by bacteria. Cyclodextrins have utility for solubilizing and stabilizing drugs. B-Cyclodextrins sulfobutyl ether is a cyclodextrin made of 7 glucose subunits, each with a negatively-charged sulfobutyl ether group attached. Using SIELC’s newly […]